General Information

  • ID:  hor006988
  • Uniprot ID:  P25031??28-175)
  • Protein name:  Regenerating islet-derived protein 3-beta 16.5 kDa form
  • Gene name:  FGF2
  • Organism:  Rattus norvegicus
  • Family:  NA
  • Source:  Animal
  • Expression:  Constitutively expressed in intestine.
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Glires (Rodents and rabbits); Rodentia; Myomorpha (mice and others); Muroidea; Muridae; Murinae; Rattus; Rattus norvegicus (Rat)
  • GO MF:  GO:0045177 apical part of cell; GO:0005615 extracellular space; GO:0032991 protein-containing complex; GO:0042588 zymogen granule
  • GO BP:  GO:0042834 peptidoglycan binding; GO:0070492 oligosaccharide binding; GO:0046872 metal ion binding; GO:0042802 identical protein binding; GO:0005179 hormone activity; GO:0019838 growth factor binding; GO:0038023 signaling receptor activity
  • GO CC:  GO:0042594 response to starvation; GO:0043434 response to peptide hormone; GO:0031667 response to nutrient levels; GO:0032355 response to estradiol; GO:0009617 response to bacterium; GO:0001934 positive regulation of protein phosphorylation; GO:0010838 positive regulation of keratinocyte proliferation; GO:0008284 positive regulation of cell population proliferation; GO:0009611 response to wounding; GO:0045617 negative regulation of keratinocyte differentiation; GO:0106015 negative regulation of inflammatory response to wounding; GO:0050829 defense response to Gram-negative bacterium; GO:1900408 negative regulation of cellular response to oxidative stress; GO:0006953 acute-phase response; GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide; GO:0071356 cellular response to tumor necrosis factor; GO:0071466 cellular response to xenobiotic stimulus; GO:0050830 defense response to Gram-positive bacterium; GO:0044849 estrous cycle; GO:1903577 cellular response

Sequence Information

  • Sequence:  DSPKKIPSARISCPKGSQAYGSYCYALFQIPQTWFDAELACQKRPEGHLVSVLNVAEASFLASMVKNTGNSYQYTWIGLHDPTLGGEPNGGGWEWSNNDIMNYVNWERNPSTALDRGFCGSLSRSSGFLRWRDTTCEVKLPYVCKFTG
  • Length:  148
  • Propeptide:  MLHRLAFPVMSWMLLSCLMLLSQVQGEDSPKKIPSARISCPKGSQAYGSYCYALFQIPQTWFDAELACQKRPEGHLVSVLNVAEASFLASMVKNTGNSYQYTWIGLHDPTLGGEPNGGGWEWSNNDIMNYVNWERNPSTALDRGFCGSLSRSSGFLRWRDTTCEVKLPYVCKFTG
  • Signal peptide:  MLHRLAFPVMSWMLLSCLMLLSQVQG
  • Modification:  
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    NA

Physical Information

Mass: Formula:
Absent amino acids: Common amino acids:
pI: Basic residues:
Polar residues: Hydrophobic residues:
Hydrophobicity: Boman Index:
Half-Life: Half-Life Yeast:
Half-Life E.Coli: Aliphatic Index
Instability Index: Extinction Coefficient cystines:
Absorbance 280nm:

Literature

  • PubMed ID:  NA
  • Title:  NA